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Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use

Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use

Recruiting
21 years and older
All
Phase N/A

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Overview

This study will compare the efficacy of telemedicine-delivered cognitive behavioral therapy for insomnia tailored for people using cannabis for sleep (CBTi-CB-TM) to telemedicine-delivered sleep hygiene education (SHE-TM) on sleep, cannabis use, and daytime functioning. We will also evaluate the effects of CBTi-CB-TM on fundamental sleep regulatory system - homeostatic sleep drive - and its association with clinical outcomes.

Eligibility

INCLUSION CRITERIA

  • 21 years of age and older, the age needed to obtain full legal access to cannabis in Michigan
  • self-reported chronic insomnia (nighttime symptoms of difficulty initiating and/or maintaining sleep and/or early morning awakenings on ≥3 nights for ≥3 months with daytime impairment), consistent with DSM-5 diagnosis of Insomnia Disorder
  • Insomnia Severity Index (ISI) score ≥11, indicative of at least "mild" insomnia
  • a positive urine drug screen (UDS) for cannabis33
  • self-reported use of cannabis at least three times weekly for the past month
  • stable residence (e.g., stable sleep arrangements), consistent access to Wi-Fi, and ability to travel to Ann Arbor for sleep laboratory assessments

EXCLUSION CRITERIA

  • individuals who do not understand English
  • individuals judged unable to provide informed consent (e.g., intoxication, mental incompetence)
  • diagnosis or high suspicion of a sleep disorder other than insomnia
  • lifetime diagnosis of psychotic disorder or bipolar disorder; current post-traumatic stress disorder that directly interferes with sleep
  • terminal or progressive physical illness (e.g., cancer) or neurological degenerative disease (e.g., dementia)
  • use of medications known to have initiated their insomnia (e.g., steroids)
  • previous receipt of CBTi
  • self-reported pregnancy
  • self-reported regular work schedule of rotating or night (3rd) shift work.

Study details
    Insomnia

NCT05814822

University of Michigan

14 July 2025

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