Image

Defining the Potency of DTG/3TC for Suppressed HIV Patients in Real-life: the DUALING Study

Recruiting
18 years of age
Both
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

Powered by AI

Overview

This study aims to determine real-life clinical efficacy of virally suppressed patienst switching to DTG/3TC compared to DTG triple drug cART controls

Description

Dolutegravir (DTG) based dual antiretroviral therapy constitutes a paradigm shift from triple drug based therapy. Data outside clinical trials are scarce. This study evaluates the value of DTG/3TC in real life.

Eligibility

Inclusion Criteria: 

        Plasma HIVRNA <50c/mL on triple drug cART regimen including 2NRTI In care in a HIV
        treatment center in the Netherlands Consented to ATHENA participation
        Exclusion Criteria:
        Documented mutations associated with 3TC or DTG resistance of at least low level Documented
        inadherence by the treating physician or HepB coinfection (cases only)

Study details

Hiv

NCT04707326

Erasmus Medical Center

25 January 2024

Contact a study center
Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.