Overview
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
Eligibility
Inclusion Criteria:
- Group 1: Patients with stage IA-IIA cutaneous T cell lymphoma
- Group 2: Patients with stage IIB and above cutaneous T cell lymphoma
- Group 3: Patients with CD30+ lymphoproliferative disorder including lymphomatoid papulosis and cutaneous anaplastic large cell lymphoma
- Group 4: Patients with plaque psoriasis with BSA>5% on routine phototherapy per standard of care
- Group 5: Patients with moderate to severe atopic dermatitis on routine bleach bath therapy per standard of care
- Group 6: Healthy individuals without the above skin conditions, similar age and sex distribution to the patients with cutaneous T cell lymphoma
- All Groups: subjects who are age 18-89 years of age at time of enrollment
- All Groups: Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443).
Exclusion Criteria:
- All Groups: Subjects who are younger than 18 years of age or older than 90 years of age
- All Groups: Subjects who are unable to give consent
- Patients currently on systemic antibiotics or recent (within past 4 weeks) exposure to systemic antibiotics
- We will not recruit the following populations: adults unable to consent, individuals who are not yet adults (infants, children, teenagers), pregnant women, prisoners and other vulnerable populations.