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Prognosis of Cerebral Small Vessel Disease

Prognosis of Cerebral Small Vessel Disease

Recruiting
16 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation.

The aim of this prospective, observational cohort study is to determine the risk of different outcome events among patients with SVD according to the type of index presentation.

Eligibility

Inclusion Criteria:

  • Hypertensive deep perforator arteriolopathy (DPA), clinically symptomatic with either ICH, ischaemic stroke, cognitive impairment or severe radiological manifestation (Fazekas ≥II)
  • Cerebral amyloid angiopathy (CAA according to modified Boston or Edinburgh criteria), clinically symptomatic with either ICH (including cSAH), amyloid spells, cognitive impairment or severe radiological manifestation (CMB≥2)
  • Other SVD (i.e. CADASIL or other sporadic or genetic SVD)

Exclusion Criteria:

  • Life expectancy of <6 months due to not-SVD related causes (i.e. cancer)
  • Patient is unlikely to attend follow-up visits

Study details
    Cerebral Amyloid Angiopathy
    Small Vessel Cerebrovascular Disease
    Cadasil
    CAA - Cerebral Amyloid Angiopathy

NCT05734378

Insel Gruppe AG, University Hospital Bern

25 January 2024

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