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Cerebral Small Vessel Disease Registry Study

Cerebral Small Vessel Disease Registry Study

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Small Vessel Disease (CSVD) and in a prospective multicenter study, to assess the clinical, genetic and epigenetic features of patients with CSVD, , to find independent imaging markers, and to optimize clinical management.

Eligibility

Inclusion Criteria:

  1. Sign informed consent.
  2. Age>18
  3. At least one of the following CSVD MRI characteristics: ①recent small subcortical infarct;②lacune of presumed vascular origin;③white matter hypertensity of presumed vascular origin;④perivascular space;⑤cerebral microbleeds;⑥brain atrophy

Exclusion Criteria:

  1. Unable to cooperate with inspectors
  2. Non-vascular white matter lesions
  3. Other cognitive diseases (such as alzheimer's disease, Parkinson's disease or thyroid disease)
  4. Serious systemic illness, such as heart, liver, kidney disease or major mental illness
  5. Contraindications for imaging examination

Study details
    Cerebral Small Vessel Diseases

NCT04318119

Bin Cai

25 January 2024

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