Overview
The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.
Eligibility
Inclusion Criteria:
- Single qualifying stroke event as confirmed by CT or MRI
- At least 1 month post stroke
- Score of at least 2-/5 on Manual Muscle Test for wrist flexors or extensors, indicating adequate movement to complete robotic device use
- Able to follow written instructions
Exclusion Criteria:
- Prior arm injury impacting available passive or active range of motion or significant arm pain with movement
- Underlying brain pathologies such as metastatic or primary brain malignancies, comorbid multiple sclerosis, etc.
- Prior significant drug or alcohol abuse
- Diagnosed with dementia
- Pre-stroke baseline modified Rankin Scale (mRS) >3
- History of seizure/epilepsy
- History of clinically significant ischemic or hemorrhagic stroke prior to index stroke resulting in prior arm injury or weakness.
- Pregnancy
- Contraindication to MRI or Transcranial Magnetic Stimulation (TMS).
- Medical instability assessed by the treating stroke physician to participate to the study.