Overview
To observe the sedative effect of continuous infusion of remidazolam in elderly patients undergoing colonoscopic polypectomy.
Description
To observe the sedative effect of continuous infusion of remidazolam in elderly patients undergoing colonoscopic polypectomy, and to screen the optimal dose of remidazolam, in order to provide a more reasonable and safe sedative and analgesic drug regimen for elderly outpatients undergoing colonoscopic polypectomy.
Eligibility
Inclusion Criteria:
- Age 60-80 years old;
- ASA Level I - III;
- Operation time: 15min~1h;
- BMI18.0-29.9；
Exclusion Criteria:
- Emergency surgery;
- Patients with high risk of gastric satiety and reflux aspiration;
- Allergies to benzodiazepines and opioids;
- Those who have taken sedative, analgesic, or antidepressant drugs within 24 hours;
- Abnormal liver and kidney function;
- Previous drug use history;
- Recently participated in other clinical studies;
- Patients who cannot cooperate with communication.