Overview
The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization
Eligibility
Inclusion Criteria:
- Age 20 and more
- Diagnosed angina or angina equivalent symptom or positive exercise treadmill test
- Patients with intermediate- or high-risk probability of CAD defined by Diamond and Forester
- 70 % stenosis or more in coronary CTA
- Willing to provide informed, written consent
Exclusion Criteria:
- Requirement for surgical procedure
- Cardiogenic shock and/or need for mechanical/pharmacologic hemodynamic support
- Recent STEMI (<5 days)
- Non STEMI, if the cardiac troponin is not stable or starting to decline
- Left ventricular ejection fraction <30%
- Life expectancy <2 years
- Impaired renal function with an effective glomerular filtration rate less than 30mL/min/1.73 ㎡ or creatinine more than 2.0 mg/dL
- Undergoing evaluation for organ transplantation
- Participation or planned participation in another cardiovascular clinical trial
- Pregnancy
- Inability to take dual antiplatelet therapy for six months
- Previous CABG
- Left main disease requiring revascularization
- Any target lesion with in-stent restenosis
- NYHA class 3 or 4a
- Severe and persistent angina with severe limitation in everyday living activities (Canadian Cardiovascular Society grading Class IV)