Overview
This is a follow-up study to investigate the long-term safety and explore efficacy of SMUP-IA-01, for the treatment of Knee Osteoarthritis. Subjects who participated in and completed the initial stage of the Phase I trial (NCT04037345 ) will be followed-up until 60 months.
Description
The subjects will be followed up at 6-month, 12-month, 24-month, 36-month, 48-month and 60-month after the initial administration of SMUP-IA-01.
Eligibility
Inclusion Criteria:
- Subject who completed the safety and explore efficacy evaluations in SMUP-IA-01 Phase I clinical trial.
- Subjects who have been treated with either SMUP-IA-01 at least 6 months ago.
- Subjects who voluntarily decided to participate and signed the consent form after receiving explanations on the clinical trial.
Exclusion Criteria:
- Subjects who were not enrolled in phase 1 clinical trial of SMUP-IA-01 for assessing safety and explore efficacy.
- Other subjects, excluding those listed above, who were deemed unsuitable by the PI