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Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch

Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch

Recruiting
18 years and older
All
Phase N/A
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Overview

The purpose of the study is to understand the composition of the nerves supplying the facet joints in low back.

Description

After written informed consent, the nerves supplying the facet joints - lumbar dorsal rami and its medial branches, will be harvested when they are exposed during spinal surgery. These nerves will be fixed, washed and further dissected to enable smaller sections. The cut section will be stained and subjected to analysis of overall cross-sectional area and presence of connective tissue sheaths under light microscope.

Eligibility

Inclusion Criteria:

  • Be aged 18 or over
  • be able to give informed consent
  • scheduled to undergo lumbar spinal surgery

Exclusion Criteria:

  • Children under 18 years old
  • Vulnerable adults
  • Adults with incapacity
  • Inability to provide informed consent
  • History of previous spinal surgery
  • history of previous RF ablation for low back pain
  • has COVID-19 or displaying symptoms of COVID-19

Study details
    Lumbar Facet Arthrosis
    Nerve Degeneration

NCT05091112

University of Aberdeen

25 January 2024

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