Overview
Interventional, comparative, randomized, controlled study versus standard treatment, in 3 parallel groups, monocentric, aiming to demonstrate the superiority of preoperative cryoneurolysis versus no procedure, in patients operated on for knee arthroplasty and receiving standard analgesia.
Eligibility
Inclusion Criteria:
- Age ≥ 18 years and ≤ 80 years;
- Patient to undergo prosthetic knee surgery;
- Patient in good health (ASA score 1 to 3);
- Patient able to understand the information related to the study, read the information leaflet and agree to sign the consent form.
Exclusion Criteria:
- Known intolerance to any of the products administered during surgery or cryoneurolysis;
- Patient with an electric implant;
- Patient with a contraindication to cryoanalgesia (coagulation disorders, infections, nerve damage);
- Drug addict patient;
- Intervention on septic bone;
- Chronic renal failure (creatinine clearance <30 mL / min);
- History of cryoglobulinemia, cold urticaria or Raynaud's syndrome;
- Pregnant or breastfeeding woman;
- Patient under guardianship or curatorship, or under a regime of deprivation of liberty;
- Patient participating in another clinical trial, or in a period of exclusion from another clinical trial;
- Patient not beneficiary of a social security scheme.