Overview

Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added.

MRI of routine care includes at least the following sequences:

• 3D T1 TFE (2 minutes)
• T2 TSE (2 minutes)
• 3D FLAIR (3 minutes)

The sequences added by the research lasting 25 minutes are:

• SWI QSM 1.0iso 8 echoes (10 minutes)
• SWI QSM 1.0iso 8 echoes CS 6 (7 minutes)
• SWI QSM 1.0iso 8 echoes CS 9 (5 minutes)
• SWI QSM 1.0iso 8 echoes CS 12 (3 minutes)

Eligibility

Inclusion Criteria:

For patients with MS:

• Patient over 18 years old
• Presenting MS defined according to McDonald's revised criteria for spatial and temporal clinical or radiological dissemination [16],
• Should benefit as part of the care of an MRI examination with or without injection of gadolinium
• Express consent to participate in the study
• Affiliate or beneficiary of a social security scheme

        For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS
        disease:
          -  Patient over 18 years old
          -  Should benefit as part of the care of an MRI examination with or without injection of
             gadolinium
          -  Express consent to participate in the study
          -  Affiliate or beneficiary of a social security scheme
        Exclusion Criteria:
          -  For patients with MS:
          -  Patient benefiting from a legal protection measure
          -  Pregnant or breastfeeding woman
        For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS
        disease:
          -  Patient benefiting from a legal protection measure
          -  Pregnant or breastfeeding woman
          -  Patient with inflammatory and / or demyelinating pathology of the CNS
        Secondary exclusion criteria :
          -  Motion artefact not allowing interpretation of images
          -  Patient who did not perform one of the following sequences: 3D T1 TFE, 3D FLAIR (for
             MS patients), SWI QSM 1.0iso 8 echoes.
        Secondarily excluded patients will be replaced.