Overview
Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added.
MRI of routine care includes at least the following sequences:
- 3D T1 TFE (2 minutes)
- T2 TSE (2 minutes)
- 3D FLAIR (3 minutes)
The sequences added by the research lasting 25 minutes are:
- SWI QSM 1.0iso 8 echoes (10 minutes)
- SWI QSM 1.0iso 8 echoes CS 6 (7 minutes)
- SWI QSM 1.0iso 8 echoes CS 9 (5 minutes)
- SWI QSM 1.0iso 8 echoes CS 12 (3 minutes)
Description
Patients who have agreed to participate in the study will complete the MRI protocol as part of routine care, to which a maximum of four additional 25-minute sequences will be added.
MRI of routine care includes at least the following sequences:
- 3D T1 TFE (2 minutes)
- T2 TSE (2 minutes)
- 3D FLAIR (3 minutes)
The sequences added by the research lasting 25 minutes are:
- SWI QSM 1.0iso 8 echoes (10 minutes)
- SWI QSM 1.0iso 8 echoes CS 6 (7 minutes)
- SWI QSM 1.0iso 8 echoes CS 9 (5 minutes)
- SWI QSM 1.0iso 8 echoes CS 12 (3 minutes)
Eligibility
Inclusion Criteria:
For patients with MS:
- Patient over 18 years old
- Presenting MS defined according to McDonald's revised criteria for spatial and temporal clinical or radiological dissemination [16],
- Should benefit as part of the care of an MRI examination with or without injection of gadolinium
- Express consent to participate in the study
- Affiliate or beneficiary of a social security scheme
For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS
disease:
- Patient over 18 years old
- Should benefit as part of the care of an MRI examination with or without injection of
gadolinium
- Express consent to participate in the study
- Affiliate or beneficiary of a social security scheme
Exclusion Criteria:
- For patients with MS:
- Patient benefiting from a legal protection measure
- Pregnant or breastfeeding woman
For patients with an indication to undergo a brain MRI and at low risk of inflammatory CNS
disease:
- Patient benefiting from a legal protection measure
- Pregnant or breastfeeding woman
- Patient with inflammatory and / or demyelinating pathology of the CNS
Secondary exclusion criteria :
- Motion artefact not allowing interpretation of images
- Patient who did not perform one of the following sequences: 3D T1 TFE, 3D FLAIR (for
MS patients), SWI QSM 1.0iso 8 echoes.
Secondarily excluded patients will be replaced.