Overview
The goal of this interventional study is to document the importance of HIV-related disabilities, notably the frequency / nature of functional limitations, neurocognitive impairments, and restrictions of social participation in adults living with HIV aged 40 and older.
Participants will undergo a comprehensive set of cognitive and functional assessments, and approximately twenty particpants will be asked to participate in an anthropological survey conducted through structured interviews.
Researchers will a group of people living with HIV and o reference group without HIV infection.
Description
This is a mixed-methods study combining a cross-sectional study during which clinical evaluations, functional tests, and quantitative evaluations by questionnaire relating to disability (WHODAS, HDQ), depression (PHQ-9) will be conducted. and an anthropological survey. The study takes place in the Abobo district, Abidjan, in two health centers.
The quantitative evaluation will concern 300 people living wiht HIV (PLHIV) receiving antiretroviral therapy and followed at the Avocatier health facility (FSU) and the El Rapha medical health centre (CMS), in the Abobo district, Abidjan. A comparison group of adults without HIV infection of similar sex and age distribution will also be included as a reference group (n = 150).
The qualitative research will include around 20 PLHIV selected so that enough diversity is represented (sex, age, family situation). It will be based on conducting interviews to examine how the practice of physical activity is perceived culturally and socially and to determine the factors that may influence the implementation of this type of activity.
Eligibility
Inclusion Criteria:
Participants living with HIV:
- Age ≥40 years
- Documented HIV-infection
- Combined ART for ≥12 months
- Written consent to participate to the study
- Controls
- Age ≥40 years
- Negative HIV test within the last 12 months;
- Living in Abobo area
- Written consent to participate to the study
Exclusion Criteria:
Participants living with HIV:
- HIV infection with HIV-2 type only
- Any clinical symptoms suggesting an acute infection
- Any life-threatening pathology in the short term or any pathology not allowing
participation in the study
- Controls
- Any clinical symptoms suggesting an acute infection
- Any life-threatening pathology in the short term or any pathology not allowing participation in the study