Overview

The purpose of this study is to determine the effects of active transcranial direct current stimulation (tDCS) paired with active mindfulness-based meditation (MBM) on clinical pain,osteo arthritis (OA)-related clinical symptoms, physiopsychological pain processing and participant satisfaction with treatment in patients with knee OA.

Eligibility

Inclusion Criteria:

• have symptomatic knee OA based on American College of Rheumatology clinical criteria
• have had knee OA pain in the past 3 months with an average of at least 30 on a 0-100 NRS for pain,
• can speak and read English
• have no plan to change medication regimens for pain throughout the trial

Exclusion Criteria:

• history of brain surgery, brain tumor, seizure, stroke, or intracranial metal implantation
• systemic rheumatic disorders, including rheumatoid arthritis,systemic lupus erythematosus, and fibromyalgia
• alcohol/substance abuse
• diminished cognitive function that would interfere with understanding study procedures (i.e., Mini-Mental Status Exam score ≤ 23)
• pregnancy or lactation
• prosthetic knee replacement or non-arthroscopic surgery to the affected knee
• hospitalization within the preceding year for psychiatric illness
• no access to a device that can be used for secure videoconferencing for real-time remote supervision.