Overview

The Change Database is a prospective, observational multi-center disease registry, which will collect data on patients with chronic thromboembolic pulmonary hypertension (CTEPH) in China. It aims to illustrate the epidemiology, management and long-term outcomes of CTEPH.

Eligibility

Inclusion Criteria:

1. Patients must be diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH)
2. Patients must be willing to provide informed consent
3. Patients must meet the following criteria for CTEPH:

        a mean pulmonary artery pressures (mPAP) ≥20 mmHg combined with a pulmonary vascular
        resistance (PVR) ≥ 3 WU and pulmonary arterial wedge pressure (PAWP)≤ 15 mmHg documented at
        right heart catheterization with radiographic evidence of organized thrombi involving the
        pulmonary arteries after 3 months of effective anticoagulation.
        Exclusion Criteria:
          1. Main cause of PH other than CTEPH
          2. Participation in a therapeutic clinical trial with an unknown drug;
          3. Withdrawal or lack of informed consent.