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The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

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18 years and older
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Phase N/A

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Overview

This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

Description

The study is a non-randomised, controlled, cross-sectional study of diseased human carotid, femoral and abdominal aortic tissue.

Eligibility

Inclusion Criteria:

  • Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
  • Able to provide informed consent.

Exclusion Criteria:

  • Patients that are unable to give informed consent.
  • Seriously ill/unconscious patients.

Study details
    Vascular Diseases

NCT05802706

University Hospital of Limerick

25 April 2025

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