Overview
This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.
Description
The study is a non-randomised, controlled, cross-sectional study of diseased human carotid, femoral and abdominal aortic tissue.
Eligibility
Inclusion Criteria:
- Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
- Able to provide informed consent.
Exclusion Criteria:
- Patients that are unable to give informed consent.
- Seriously ill/unconscious patients.