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A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

Recruiting
18 years and older
All
Phase N/A

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Overview

The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery. The researchers are particularly interested in the heart function and blood flow changes in people who experience low blood pressure (hypotension) after receiving anesthesia.

Eligibility

Inclusion Criteria:

  • Adult patients ≥ 18 years of age requiring general anesthesia for surgery
  • Intubation required for anesthetic management / surgery
  • Anticipated prep time before incision of 20 minutes
  • Baseline MAP >70mmHg

Exclusion Criteria:

  • History of coronary artery disease
  • History of cardiac disease (e.g., HTN, arrythmias, valvular and structural abnormalities)
  • History of peripheral artery occlusive disease
  • Beta-blocker use
  • Anti-hypertensive medication use
  • Patients with epidural, spinal, paravertebral, serratus blocks preoperatively
  • Patients requiring rapid sequence induction (where intubation occurs concurrently with induction)
  • Emergency surgery

Study details
    Anesthesia

NCT05954832

Memorial Sloan Kettering Cancer Center

4 July 2025

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FAQs

Learn more about clinical trials

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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