Image

A Modified Esophagogastric Reconstruction Method After Laparoscopic Proximal Gastrectomy

Recruiting
18 - 75 years of age
Both
Phase N/A

Powered by AI

Overview

The double-flap technique (DFT) is an effective digestive tract reconstruction method after proximal gastrectomy (PG) to reduce the incidence of postoperative reflux esophagitis. But its clinical application is restricted due to the technical complexity. Our surgical team devise a modified esophagogastric reconstructive method which we term the "arch-bridge-type" reconstruction based on the principle of DFT. The aim of this single-arm prospective study is to assess the safety and feasibility of the "arch-bridge-type" reconstruction after PG.

Description

  1. The lymphadenectomy is performed according to the Japanese Gastric Cancer Treatment Guidelines.
  2. Transection of the esophagus is performed using a linear stapler 2cm away from the proximal end of the tumor.
  3. Creating the seromuscular flap ("arch-bridge"):

(1) The stomach is resected by a linear stapling device. (2) A "匚" shaped seromuscularflap (3.0cm×4.0cm) is created utilizing electrocautery extracorporeally by dissecting submocosal and muscular layer of the anterior wall of the remnant stomach.

(3) The opening of the flap is interrupted sutured by 4-0 absorbable suture, then the "arch-bridge" is created.

4.The remnant stomach is then inserted into the abdominal cavity, and pneumoperitoneum is re-established to perform the intracorporeal anastomosis.

Eligibility

Inclusion Criteria:

  • histologically proven proximal gastric cancer or adenocarcinoma of esophagogastric junction
  • diameter of the tumor less than 4cm
  • ECOG performance status score ≤2
  • no distant metastasis
  • informed consent is signed

Exclusion Criteria:

  • metastatic gastric cancer or metastatic adenocarcinoma of esophagogastric junction
  • remnant gastric cancer
  • patient requires emergency surgery

Study details

Proximal Gastric Adenocarcinoma, Adenocarcinoma of Esophagogastric Junction, Anastomosis

NCT05829213

Peking University

25 January 2024

Step 1 Get in touch with the nearest study center
What happens next?
  • You can expect the study team to contact you via email or phone in the next few days.
  • Sign up as volunteer  to help accelerate the development of new treatments and to get notified about similar trials.

You are contacting

Investigator Avatar

Primary Contact

site

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.