Overview
This study is a randomized, controlled trial. A total of 92 patients will be randomized to receive sufentanil or remifentanil during extracranial-intracranial bypass surgery.
Eligibility
Inclusion Criteria:
- Patients who undergo elective extracranial-intracranial bypass surgery
- American Society of Anesthesiologists grade 1,2,3
- Age \> 18 years old
Exclusion Criteria:
- Refuse to participate to the study
- American Society of Anesthesiologists grade 4
- Body Mass Index \< 18.5 kg/m2 or \> 35 kg/m2
- Allergic history of opioid
- pregnant
- MAO Inhibitor user
- Severe respiratory insufficiency


