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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,247 clinical trials
J Jens Kastrup, MD DMSc

Adipose Derived Mesenchymal Cell Treatment in Lungtransplantation

To investigate safety of treatment with allogeneic adipose tissue-derived mesenchymal stromal cells (ASCs) in patients undergoing lung transplantation, to evaluate whether the treatment can reduce host immunological reaction towards the graft, and to reduce the ischemic reperfusion-injury after transplantation.

18 - 70 years of age Both Phase 1/2
M Murat Bilgi, MD

Caudal Epidural Steroid and Trigger Point Injection

This prospective randomized study will be conducted in Bolu Abant İzzet Baysal University Hospital. Chronic low back and hip pain 72 patients aged between 18-70 years will be included in the study. The primary output of our study was NRS scores. The study of Manchikanti. L et al. (control group …

18 - 70 years of age Both Phase 4
L Linton Cuff

Administration of Hydroxychloroquine (Plaquenil) to African Americans and Hispanics for the Treatment of Mild to Severe Ulcerative Colitis

The objective of this study is to assess the efficacy of hydroxychloroquine (HCQ) when combined with Mesalamine in reducing clinical and histologic disease activity in patients who have active mild to severe Ulcerative Colitis (UC) and also to assess the immunological effects of hydroxychloroquine in this population. These outcomes will …

18 - 100 years of age Both Phase 1/2
B Badhma Valaiyapathi, MBBS, MPH

Retraining and Control Therapy (ReACT) R33 Phase

The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of pediatric psychogenic non-epileptic seizures (PNES, episodes resembling epileptic seizures but with no correlated epileptiform activity). 11-18-year-olds …

11 - 18 years of age Both Phase N/A
R Robert DeLorenzo, MD

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute suicidality in the context of the Emergency Department setting. This study will assess a combination of a …

18 - 70 years of age Both Phase 2/3
R Rey Manuel Silva Mendez

Screening for Neonatal Jaundice With a Mobile Health Device: a Validation Study in Oaxaca, Mexico.

The performance and accuracy of the smartphone application (app) Picterus Jaundice Pro (PicterusJP) will be validated by a cross-sectional study conducted in low resource settings in Mexico. Physics-based and machine learning-based models will be used to analyze the images obtained with the app and its performance will be compared.

1 - 14 years of age Both Phase N/A
F Furkan Özdemir, MSc., PT.

Effect of Calisthenic Exercise Training Combined With Aerobic Exercise in Patients With Dyslipidemia

Dyslipidemia is expressed as the serum concentration of lipid molecules with different structures outside the normal level. Deviation of serum lipid level from normal is accepted as the primary or most important factor in various cardiac and metabolic diseases, especially atherosclerosis. Dyslipidemia-related cardiovascular structure change is accepted as an important …

18 - 65 years of age Both Phase N/A
G Gehan Morsy, MD

Driving Pressure Guided Ventilation Versus Conventional Lung Protective Strategy in Morbid Obese Patients Undergoing Laparoscopic Bariatric Surgery

This study will be conducted to evaluate the effect of driving pressure guided ventilation compared with conventional protective lung ventilation during laparoscopic bariatric surgeries in morbid obese patients. the primary outcome: Intraoperative oxygenation measured by the arterial partial pressure of oxygen (PaO2). the secondary outcome: incidence of early postoperative pulmonary …

18 - 60 years of age Both Phase N/A

Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)

The main purpose of the study is to determine noninvasive markers of brain involvement in Chagas disease. In a subgroup of patients with high intensity transient signals (HITS) on transcranial Doppler monitorization, the investigators aim to determine the efficacy and safety of aspirin in preventing microembolization in patients with no …

18 - 100 years of age Both Phase 4
J John Dreixler, PhD

Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women

This is a single-center, open-label pilot study looking at how Guideline-directed management and therapy (GDMP) in post-partum women with preeclampsia can improve Global Longitudinal Strain (GLS).

18 - 45 years of age Female Phase N/A

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