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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,251 clinical trials

Dyspnea and Cardiotoxicity in Multiple Myeloma Patients Who Receive Carfilzomib

This study will explore why some multiple myeloma patients who receive carfilzomib (an anti-cancer medication) experience shortness of breath while others do not. The purpose of this research is to gather information on the effectiveness of the EndoPAT device, which is FDA-approved to assess the health of a patient's blood …

18 - 100 years of age Both Phase N/A
A Anna Duong

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

The investigators will utilize a systematic approach for the diagnostic evaluation of patients to identify characteristics which may distinguish between Primary Immunodeficiency (PID) disorders versus Primary Ciliary Dyskinesia (PCD).

5 - 45 years of age Both Phase N/A
R Rana i MITRI-FRANGIEH

Analysis of the Molecular Composition of Tubal Cilia in Patients With or Without Ectopic Pregnancy

Primary Ciliary Dyskinesia associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of mobility of sperm but very little data on the structure and function of tubal cilia in women

18 - 100 years of age Female Phase N/A
S Sandra Pepin

Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies

Though common, morbidities related to upper airway disease in primary ciliary dyskinesia (PCD) and primary immunodeficiencies (PID) have not been fully characterized. These conditions can be difficult to distinguish due to their overlapping phenotypes. The sinonasal and middle ear features are often identified as most problematic by patients and their …

5 - 45 years of age Both Phase N/A
V Vicky Rubini

High Flow Nasal Cannulae vs Venturi Mask in Respiratory Failure Due to Pneumonia

The primary objective of this study is to compare the efficacy of treatment with HFNC (group compared to administration of oxygen therapy by Venturi mask (group B, standard therapy) in terms of reaching of endotracheal intubation criteria during acute respiratory failure due to severe pneumonia. Inclusion Criteria: Respiratory rate (RR) …

18 - 100 years of age Both Phase N/A
D David Hiltzik, MD

Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?

The objective of this study is to compare the effectiveness of batten grafts plus septoplasty and turbinate reduction (intervention arm) compared to septoplasty and turbinate reduction alone (control arm), both in terms of subjective and objective assessments.

18 - 100 years of age Both Phase N/A
J Jacco J. de Haan, MD, PhD

Eating Experience at the Comprehensive Cancer Center Wards - a Qualitative Study

In hospitalized patients with cancer treated with systemic therapy, semi-structured in-depth interviews will be performed. Topics that will be discussed are eating-related complaints, the taste and smell of the offered hospital food, the choice in hospital food, the ambience during the eating moments, the use of protein-enriched snacks, the difference …

18 - 100 years of age Both Phase N/A
S Samir Gupta, MD, MSc

Personalized Smoking Cessation Infographic in COPD

This study assesses the effect of a personalized smoking cessation infographic on physician smoking cessation counseling rates and smoking cessation pharmacotherapy prescription rates. The study assesses the difference in physician behaviour using an interrupted time series analysis (one-year pre vs. one-year post-intervention). General practitioners, nurse practitioners and respirologists who refer …

18 - 100 years of age Both Phase N/A
A Ann Klipsch, RN

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Cholestasis is a condition in which bile is not properly transported from the liver to the small intestine. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acid synthesis and metabolism defects, and progressive familial intrahepatic cholestasis …

- 25 years of age Both Phase N/A
C Claire Finnie

Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis

The purpose of this study is to assess the efficacy of using intelligent volume assured pressure support (iVAPS-AE) versus spontaneous timed (ST) modes of non-invasive ventilation (NIV) in patients diagnosed with amyotrophic lateral sclerosis (ALS). The investigators believe that the use of iVAPS-AE mode NIV over a 90 day period …

18 - 100 years of age Both Phase N/A

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