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Inflammation Clinical Trials

A listing of Inflammation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,945 clinical trials
N Ning Shi, Master

A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-D

The purpose of this study is to evaluate the efficacy and safety of Live SK08 Powder compared with placebo in the treatment of participants with irritable bowel syndrome with diarrhea.

18 - 70 years of age Both Phase 3
C Chong Lei, MD

PANDORA: Paravertebral AdjuNctive DexamethasOne Palmitate Reducing Chronic Pain After Caridiac Surgery

The goal of this single-center, prospective, double-blind randomized controlled clinical trial is to explore preventive interventions for chronic postoperative pain (CPSP) in patients undergoing minimally invasive cardiac surgery. The main questions it aims to answer is: the incidence of CPSP is high and severe, and there is no safe and …

18 - 65 years of age Both Phase N/A

Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.

18 - 100 years of age Both Phase 3
E Elena Sinkovskaya, MD

Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring …

18 - 100 years of age Female Phase 3

Pain, Inflammation and Opioid Craving

The goal of this study is to investigate the association between response to pain and opioid craving in people with opioid use disorder. In this study, adults with opioid use disorder will be randomized to one of two brief education sessions followed by an assessment of response to pain. Investigators …

18 - 100 years of age Both Phase N/A
S Sandra Mukasa, MD

Atorvastatin to Reduce Inflammation After Tuberculosis Treatment Completion

This is a proof-of-concept phase IIB, double-blind, randomized, placebo-controlled trial to evaluate the safety and efficacy of 40 mg atorvastatin to reduce persistent lung inflammation after successful TB treatment completion in HIV-infected and HIV-uninfected adults measured by PET/CT.

18 - 65 years of age Both Phase 2/3
J Jodi Kennedy

Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery

This is a multicenter, double-masked, randomized, vehicle-controlled, parallel-comparison study conducted at sites in the United States (US) in subjects undergoing routine unilateral cataract extraction and lens replacement (CELR) surgery via phacoemulsification

21 - 100 years of age Both Phase 2
P Panagiota Klentrou, PhD

Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes

Physical activity and dairy consumption during growth and development are each known to improve peak bone mass in young adults. Peak bone mass, the maximum amount of bone a person will have in their lifetime, is typically reached in the early 20's in females and late 20's in males. However, …

15 - 22 years of age Both Phase N/A
G Gergely Toldi, Dr

Anakinra for Preterm Infants Pilot

Phase I/II study of anakinra to prevent the impact of perinatal inflammation in extremely premature infants.

24 - 28 years of age Both Phase 1/2

Single and Multiple Ascending Oral Doses of Avenanthramide

Avenanthramides (AVA) are di-phenolic compounds found only in oats and are of interest due to suggested bioactivities, including antioxidant and anti-inflammatory effects in vitro and in vivo. Published data suggests that polyphenols can work as modifiers of signal transduction pathways to elicit their beneficial effects. These natural compounds express anti-inflammatory …

18 - 60 years of age Both Phase 1/2

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