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Neurologic Disorders Clinical Trials

A listing of Neurologic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 6,633 clinical trials
K Kristina Simonyan, MD, PhD

Brain-Computer Interfaces in Laryngeal Dystonia

The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.

18 - 80 years of age Both Phase N/A
F Furkan Özdemir, MSc., PT.

Effect of Calisthenic Exercise Training Combined With Aerobic Exercise in Patients With Dyslipidemia

Dyslipidemia is expressed as the serum concentration of lipid molecules with different structures outside the normal level. Deviation of serum lipid level from normal is accepted as the primary or most important factor in various cardiac and metabolic diseases, especially atherosclerosis. Dyslipidemia-related cardiovascular structure change is accepted as an important …

18 - 65 years of age Both Phase N/A
S Siti Zaleha Sahibulddin

UCMSCs as Treatment for Patients With Acute Ischemic Stroke (Stroke Neuroncell-EX)

The primary objective of this study is to evaluate the functional recovery based on Barthel index (BI) and modified Rankin Scale (mRS) while the secondary objectives are to assess the survival and re-admission rate as well as to investigate the inflammatory response in a subclinical study within 1 year of …

18 - 100 years of age Both Phase 2/3
A Ashley Rettmann

Brain State-dependent Stimulation to Improve Movement

Repetitive transcranial magnetic stimulation (rTMS) is a powerful tool to non-invasively modulate brain circuits, brain plasticity, and behavior. This proposal will test the hypothesis that controlling behavioral state during focal multi-day rTMS of a brain region involved in grasping movements will enhance the functional specificity of the neuromodulation action among …

18 - 50 years of age Both Phase N/A
M Marjolaine WILLEMS, PH

Proteomic Study of Tears From Patients With a PAX6 Mutation

This is a single-center prospective pilot study involving the ophthalmology and medical genetics departments of the Montpellier University Hospital, and the proteomics platform of the Montpellier University Hospital. 5 patients with PAX6 pathogenic variation will be included in order to determine the proteomic profile in a tear sample associated with …

18 - 100 years of age Both Phase N/A
D Debbie E Harrington, BS

Sensorimotor Imaging for Brain-Computer Interfaces

The investigators will use fMRI to map movement activity in motor and somatosensory cortex using enriched imagery in people with chronic tetraplegia. The investigators expect that somatotopic organization of movement activity will be preserved in people with upper limb impairments, which can be quantified using the strength, area, and location …

18 - 100 years of age Both Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Main Study: Influence on Plasticity of Brain Temperature Sub-Study: Phase Triggered Paired Associative Stimulation (PAS)

Sub-Study: Phase Triggered Paired Associative Stimulation (PAS) (actively recruiting) Background -Previous research has shown that the brain s activity changes with changes in brain waves. We can study brain activity with a procedure called transcranial magnetic stimulation (TMS), a form of non-invasive brain stimulation. EEG allows for measuring ongoing brain …

18 - 35 years of age Both Phase N/A
W William P Vandertop, MD, PhD

Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma

Rationale: Chronic subdural hematoma (cSDH) is a frequently occurring disease, occurring mainly in the elderly. Surgical evacuation is effective, but also associated with life-threatening risks. In these old, often frail, patients with multi-comorbidity, surgery also comes with significant risks for future cognitive functioning and therefore, loss of independency. In five …

50 - 100 years of age Both Phase 3
O Ozlem Guzel Polat, 1

Effects of Information-Motivation-Behavioral Skills Model on Disease Management of Adolescents With Epilepsy

The adolescent's search for self-discovery and identity in physical, psychosocial, cognitive and emotional areas may become more complex with epilepsy disease management. The adolescent's burden of treatment compliance may lead to poor adherence to the disease and worsen short- and long-term health outcomes. Disease self-management in epilepsy represents the processes …

12 - 18 years of age Both Phase N/A

The Effect of Position Given to Preterms After Feeding on Gastric Residual Volume, Abdominal Oxygenation and Fractional Oxygen Extraction

This study is a PhD dissertation. In this study, the investigators aim to investigate the effects of three different positions after feeding on gastric residual volume, abdominal oxygenation using near infrared spectroscopy (NIRS), and fractional oxygen extraction values in preterm newborns.

28 - 33 years of age Both Phase N/A

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