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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,285 clinical trials
A Aderonke Abiodun, MBChB

Defining Robust Predictors of Chemotherapy Related Cardiotoxicity

Observational prospective cohort study designed for patients with gastrointestinal cancers receiving a fluoropyrimidine based chemotherapy regimen.

18 - 100 years of age Both Phase N/A
Y Yin Ting Lam, MD

The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients (EPIC-PCD)

The Ear-Nose-Throat (ENT) Prospective International Cohort of patients with Primary Ciliary Dyskinesia (EPIC-PCD) is a prospective observational clinical cohort study, set up as a multinational multi-centre study. It is embedded into routine patient care of participating reference centres for PCD and patients keep being managed according to local procedures and …

- 100 years of age Both Phase N/A
K Kelli Sullivan, MPH

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

The overall short-term goals of this project include the following: 1) identify the genes that are key to the function of respiratory cilia to protect the normal lung; and 2) the effects of genetic mutations that adversely affect ciliary function and cause primary ciliary dyskinesia (PCD), which results in life-shortening …

- 100 years of age Both Phase N/A
A Anna Duong

Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary Dyskinesia

The overall objective of this longitudinal, observational study is to provide information needed to inform the design of future interventional trials of respiratory exacerbation prevention and treatment in children and adults with primary ciliary dyskinesia (PCD).

6 - 100 years of age Both Phase N/A
I I-HSUAN CHEN, PhD

Lenvatinib Therapy in HCC Patients After LDLT

New guidelines have been successfully established to distinguish the patients who were suitable for LT. This is important for long-term recurrence free and overall survival rate. We stratified patients with PET diagnosis and fetal protein response to confirm if they were the high-risk group for HCC recurrence. According to our …

18 - 75 years of age Both Phase N/A
M Maria L Posadas-Martinez, MD

HIBA-Institutional Registry of Amyloidosis

Creating a population-based registry system Amyloidosis prospective epidemiological survey risk factors diagnosis prognosis treatment monitoring survival 2. Describe the occurrence of amyloidosis in the population of HIBA, Hospital Italiano de Buenos Aires. 3. Describe the characteristics of clinical presentation, evolution and predisposing factors of amyloidosis.

18 - 100 years of age Both Phase N/A
D David Gagnon, PharmD

Ceftriaxone to PRevent pneumOnia and inflammatTion aftEr Cardiac arresT (PROTECT)

Randomized-controlled trial and microbiome assessment to understand the risk-to-benefit ratio of prophylactic antibiotics (Ceftriaxone) vs placebo in patients with pneumonia and inflammation after cardiac arrest outside the hospital.

18 - 100 years of age Both Phase 2

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer

This is an observational study for patients with prostate cancer that will be treated with Androgen Deprivation Therapy. The study will help the investigators learn more about how these medications affect the heart and how those effects relate to patients' medical history and social determinants of health (such as race, …

18 - 100 years of age Male Phase N/A
O Oksana Kamenskaya, PhD, MD

Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort

Prospective cohort research to study the state of oxygen metabolism, reserve capabilities of cardiovascular and respiratory systems in patients with breast cancer to create a program of prevention and rehabilitation of lung damage in the process of complex treatment of the disease. The aim of the study is to study …

18 - 100 years of age Female Phase N/A
O Olga Dzhioeva

Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction

Due to the steady increase in the burden of HFpEF, especially in women, it is an important task to search for new markers and early predictors associated with the development of this disease. Nowadays, the relationship of adverse pregnancy factors with the development of long-term cardiac pathology, in particular, HFpEF, …

45 - 60 years of age Female Phase N/A

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